Novel antibiotics, amythiamicins. II. Structure elucidation of amythiamicin D.

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Novel antibiotics, amythiamicins. II. Structure elucidation of amythiamicin D.

The structure of a unique polythiazole-containing cyclic peptide antibiotic, amythiamicin D, was elucidated by chemical degradations and NMR spectral analyses. Acid hydrolysis of amythiamicin D gave one mole of glycine and three new amino acids. Structures of N-acetyl-O-methyl derivatives of these new amino acids were determined by NMR and UV spectral analyses. Connectivities of these amino aci...

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ژورنال

عنوان ژورنال: The Journal of Antibiotics

سال: 1994

ISSN: 0021-8820,1881-1469

DOI: 10.7164/antibiotics.47.1145